Your Guide to Planning Pregnancy with Lupus (SLE)

Lupus, or Systemic Lupus Erythematosus (SLE), is a chronic autoimmune disease that can impact multiple organs, including the kidneys, heart, and lungs. Planning a pregnancy requires careful preparation for women diagnosed with lupus. But with proper care and support, many women with lupus can have successful pregnancies. For optimal outcomes, consult fertility specialists and consider V Fertility Clinic’s egg freezing program in Bangkok.

Symptoms of Lupus and Their Impact on Fertility

Lupus can present with various symptoms that may fluctuate in intensity. Some of the common symptoms include fatigue and chronic pain, joint swelling and stiffness, a butterfly-shaped rash across the cheeks and nose, unexplained fever, hair loss, mouth ulcers, shortness of breath or chest pain, blood clotting disorders, and recurrent miscarriages or preterm labor. With lupus nephritis, the symptoms are foamy or bloody urine, swelling (edema), high blood pressure, and fatigue.

Considerations When Diagnosed With Lupus

Assess Disease Activity

Pregnancy should ideally be planned when lupus has been inactive or well-controlled for at least six months. Active disease at the time of conception can increase the risk of complications, including flares, preeclampsia, and preterm birth.

Review Medications

Certain lupus medications may not be safe during pregnancy. A medication review is essential to adjust treatment plans and minimize risks to the mother and the baby.

Monitor Organ Function

Lupus can affect the kidneys, liver, and heart. Regular monitoring of organ function helps identify potential issues that could complicate pregnancy.

Manage Blood Pressure

Lupus patients are at higher risk of hypertension and preeclampsia. Blood pressure management is critical before and during pregnancy.

Consult a High-Risk OB-GYB

Specialized care from a maternal-fetal medicine specialist ensures comprehensive monitoring and early intervention in case of complications.

Challenges When Planning Pregnancy with Lupus

It is recommended that lupus patients have stable disease activity for at least six months before attempting to conceive to reduce risks. However, hormonal changes during pregnancy can trigger lupus flares, potentially impacting mother and baby. Due to this, women with lupus face a higher risk of complications such as preeclampsia, preterm birth, and stillbirth. Some lupus medications are contraindicated in pregnancy and may need to be adjusted or discontinued under medical supervision.

4 Steps for a Safer Pregnancy

 

1. Get pre-pregnancy counseling: Consult a rheumatologist and OB-GYN to assess health status and create a tailored pregnancy plan.
2. Review medication: Adjust medications to minimize risks without compromising lupus control.
3. Make healthy lifestyle choices: Focus on a nutrient-dense diet, get adequate rest, and manage stress to support maternal and fetal health.

How V Fertility Clinic Can Help

For women with lupus (SLE) whose disease is not yet under control, delaying pregnancy may be necessary to ensure the safety of the mother and baby. During this time, fertility preservation options, such as egg freezing, can be considered a safeguard for future fertility.

V Fertility Clinic provides specialized care for women with chronic conditions like lupus who are planning to conceive. Our team offers comprehensive fertility assessments, individualized treatment plans, and advanced egg freezing services to support women with lupus in their reproductive journey. Book a consultation to discuss your fertility options.

 

Article by Dr.Wanakan Singhasena

References:

• Your Guide to Planning Pregnancy with Lupus (SLE). Retrieved May 8, 2025 from:

https://www.uptodate.com/contents/systemic-lupus-erythematosus-and-pregnancy-beyond-the-basics/print

• Your Guide to Planning Pregnancy with Lupus (SLE). Retrieved May 8, 2025 from:

https://www.tommys.org/pregnancy-information/planning-pregnancy/health-conditions-and-planning-pregnancy/lupus-and-planning

• Your Guide to Planning Pregnancy with Lupus (SLE). Retrieved May 8, 2025 from:

https://www.lupus.org/resources/planning-a-pregnancy-when-you-have-lupus