Today’s technology has been developed to allow spouses to retain embryos and germ cells for future use by freezing methods (Cryopreserve). It can be stored for a long time by Freezing technique with a method called Vitrification. It is a method that has been developed and is widely used today because it has very little effect on the embryo and germ cells and it can achieve the success in pregnancy, same as the use of fresh embryos or non-frozen germ cells. Patients treated with IVF or ICSI if stimulating with a large number of eggs also have the opportunity to fertilize the embryo in greater quantities. The amount of embryos that have not been used to move into the uterus in the first round must therefore be preserved by freezing. If the patient wants to do embryo transfer in the next cycle, the frozen embryo can be used without having to start the egg stimulation process. In addition, the frozen embryos, including germ cells (egg and sperm cells) can also be used in other cases where these cells must be stored first for future use such as cases of cancer patients who still want to have their own children in the future but must receive treatment that adversely affects their reproductive cell formation whether with surgery, chemotherapy, or radiotherapy.
Sperm freezing may also be used to store sperm before being used for fertilization outside the body for patients with problems and may not be able to secrete sperm on the egg collection day. In some women who have not yet decided on marriage and having children. If they are wanting to have a child at an older age, there may be a problem with poor ovarian function. They can freeze egg cells first to use if they want to have children in the future.
Benefits of sperm freezing
- For those who are undergoing sterilization by cutting the sperm duct in order to have sperm stored if there is a need to have more children in the future.
- For those who are going to be treated with chemotherapy or drugs that will have a negative effect on future sperm production
- For those who have to be treated with testicular cutting.
- For those who have a history that the father has abnormal Y-chromosome microdeletion. The type that will cause sperm production to decrease as they They may consider sperm freezing while sperm are still in good quality.
- For couples who do not have the opportunity to have sex during the time when the eggs fall due to not being together. They may consider freezing male sperm to inject into the uterus of the female during ovulation.
- For spouses who are in the treatment of IVF and the male cannot travel to collect the semen on the day that the eggs are collected from the female to fertilize. They may consider sperm freezing before the egg collection date.
- For the spouse receiving treatment for infertility with the ICSI process using sperm that must be extracted from the semen tube or cut the tissue from the testicles (PESA or TESE), then freeze the remaining sperm cells from fertilization. This will help avoid sperm penetration from the semen tube or cutting the tissue from the testicles in the next treatment cycle.
- For spouses who need to use sperm donation, freezing sperm from donors and detecting sexually transmitted diseases in donors such as HIV virus, hepatitis B virus and C after donating for 3-6 months to confirm that there is no infection before sperm use. This reduces the risk of infection with sexually transmitted diseases from the use of donated sperm.
Benefits of egg freezing
- For those who are going to be treated with chemotherapy or drugs that will have a negative effect on future ovarian function.
- For those who have a family history of menopause before the age of 40.
- For those who have religious restrictions and beliefs that do not allow freezing in the treatment of IVF. They may consider freezing the remaining egg cells from fertilization in the current treatment cycle for the next treatment cycle.
- For those who are treated with IVF and cannot store the male sperm on the day of collecting eggs. They can freeze eggs to use in future treatment cycles without requiring egg stimulation again.
- For spouses who need to use donated egg cells freezing egg from donors. Then, detect sexually transmitted diseases in donors such as HIV virus, hepatitis B virus and C after donating the virus for 3-6 months to confirm that there is no infection before using the egg cell. This reduces the risk of sexually transmitted diseases from using donated egg cells.
- For women who do not have a family and want to maintain fertility for the future because the fertility of women gets less and less with age. When the integrity of the ovaries is less, the ability to have children with their egg cells will decrease. Or for women whom it’s not possible to do Egg cell freezing while young and the quality of egg cells are still complete, it is an alternative way to treat reproductive conditions in the future.